Anti Depression pill

Discussion in 'Relationships, Discrimination, and Jealousy' started by D_electric chair, Aug 13, 2006.

  1. D_electric chair

    D_electric chair New Member

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    Have anyone here take Zoloft? Everytime I take it I get the feeling of about to throw up and dont have an appetite. Anyone experience this before?
     
  2. headbang8

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    Yep, my doctor prescribed Zoloft. It made me jittery in the same way pseudoephedrine does. Tons of side effects, including some rather tedious sexual ones.

    It's likely that you'll need to try a few of these for a while. The side effects somtimes settle down after a couple of weeks, but it can take a month or more for the antidepressant effect to kick in. In the meantime, hang in there.

    I've found the CrazyMeds website invaluable. And very amusingly written. You might want to check out Wing of Madness and Maledepression.com, too

    I've battled depression for much of my adult life. If you want to chat about it, feel free to PM me.

    Take care of yourself,

    HB8
     
  3. DC_DEEP

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    Zoloft is one of the few that was not tried on me. I have migraines, and there are no drugs designed specifically to prevent them, but they do use blood pressure meds, anti-seizure meds, and antidepressants.

    Several of the tricyclic antidepressants had no effect whatsoever. When they started me on various SSRIs, though, that's when the side effects really kicked in. The worst was Paxil. It didn't help the headaches, but after a while I realized that it was making me grind my teeth at night, and I ended up with several broken molars. When I stopped taking it, withdrawal was very unpleasant. Every time I moved, it felt like the ground was spinning. That lasted a couple of weeks. The most effective (but still not too great) was Prozac.

    Different antidepressants work differently on different people. Some are effective for some, but not others. Some have unbearable side effects for some, but not others. Most have to be taken for several weeks before any beneficial effects are noticed. Talk to you doctor (I assume you are under a doctor's care to get Zoloft) and talk to him, honestly, about what's going on. If the side effects do not level off after a week, you should consider a different medication, until you find the one that works best for you. Best of luck.
     
  4. B_horribleperson

    B_horribleperson New Member

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    thats how i feel after a night of heavy drinking.
     
  5. Heather LouAnna

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    Many antidepressants on the market today, such as Zoloft, are reinhibiting the uptake of serotonin in your brain. (If you've ever had ecstasy before, you know that taking antidepressants will feel like you're coming up on a roll, but never actually peaking.) The feeling in your stomach and the jitters are directly related to this. If you feel physically sick to the point of discomfort, there are other medications that you can take which may work just as well as Zoloft.

    If you're not physically sick though, and the affects are rather mild, I suggest you continue taking the medication until after the two week mark and you will begin to feel those adverse affects waning and see clearer skies ahead of you.

    Be prepared for sexual side effects.
     
  6. jeff black

    jeff black <img border="0" src="/images/badges/gold_member.gi

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    She said it best, folks.

    Most new meds, especially the ever popular Zoloft, do take a few weeks to get sorted out in the system. During the first 2-4 weeks, the side effects (sizziness, nausea, diarreah, headaches, loss of appetite etc,) are the most common, and are the main reason that many discontinue usage. I recommend you keep with the Zoloft. Too much vomitting or nausea could mean ur dosage is too high.
     
  7. headbang8

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    The more modern meds are effective at lower doses, which can lower the side effects. Zoloft is a pretty old drug by now.

    My fave was Edronax (reboxetene) which is available in Europe but not the USA. I found the sexual side effects intiguing--of course there was some delayed orgasm, but I found that from time to time I could come with little or no erection. And all kinds of odd sensations along the urinary tract. It got old after a while, though.
     
  8. Heather LouAnna

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    Also, you may have read articles recently that state that antidepressants cause suicide. This is absolutely accurate, and I'll tell you why.

    Many individuals who're experiencing clinical depression with suicidal ideations will be so depressed that they haven't the energy to do anything for themselves. This can be said about their diet and hygiene, in addition to any other everyday acitivities. They will have so little urge to do anything for themselves, that they wont even bother taking their own lives. Many, at this point though, will recognize that they need medication.

    Once they begin taking the medication, it gives them a boost of energy, but since the chemical imbalance in their brain is still occuring, and the medication hasn't reached the two week point (the level of stability) they will have enough strength to commit suicide. The first several weeks where one begins a new psychotopic medication must be watched carefully and not taken lightly.
     
  9. Heather LouAnna

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    This is also absolutely accurate. If I came to the point where I felt I needed to be on antidepressants, I wouldn't dare consider Zoloft or Prozac.

    Older medications that reinhibit the uptake of serotonin may also block other chemicals that your brain is creating. There are constantly new pharmaceuticals being made that are much better.

    As taken from biopsychiatry.com:

    "[SIZE=-1]Early antidepressant medications e.g. tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs) are effective because they enhance either noradrenergic or serotonergic mechanisms, or both. Unfortunately, these compounds block cholinergic, histaminergic and alpha-1-adrenergic receptor sites, interact with a number of other medications and bring about numerous undesirable side effects. Several chemically unrelated agents have been developed and introduced in the past decade to supplement the early antidepressants. These include selective inhibitors of the reuptake of serotonin (the selective serotonin reuptake inhibitors (SSRIs)) or noradrenaline (reboxetine) or both (SNRIs: milnacipran and venlafaxine), as well as drugs with distinct neurochemical profiles such as mirtazapine, nefazodone, moclobemide and tianeptine. All these newer compounds are the results of rational developmental strategies to find drugs that were as effective as the TCAs but of higher safety and tolerability profile. In spite of the remarkable structural diversity, most currently introduced antidepressants are monoamin based and modulating monoamine activity as a therapeutic strategy continues to dominate antidepressant research. It must be emphasised, however, that these newer antidepressants are far from the ideal ones, also resulting in undesirable side effects and requiring 2-6 weeks of treatment to produce therapeutic effect. Furthermore, approximately 30% of the population do not respond to current therapies. An important new development has been the emergence of potential novel mechanisms of action beyond the monoaminergic synapse. The results of recent novel developmental approaches have suggested that modulation of N-methyl-D-aspartate (NMDA), neuropeptide (substance P and corticotrophin-releasing factor) receptors and the intracellular messenger system may provide an entirely new set of potential therapeutic targets."

    All antidepressent medications that are on the legal market presently are closely related to the street drug MDMA (ecstasy).
    [/SIZE]
     
  10. D_Elijah_MorganWood

    D_Elijah_MorganWood New Member

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    I took Zoloft for a couple years with no problems and then went off it. 7 years later I resumed and it made me gain a ton of weight. Didn't happen last time. It also wasn't working for me like it did before. It works for some, not for others. Regarding the nausea, I had that at first and then it went away.
     
  11. Nelly Gay

    Nelly Gay New Member

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    Moreover, a lot of the older-style tricyclic antidepressants were potentially lethal in overdosage....
    To go to the Doctor saying you were suicidally depressed and then, to be handed, a lethal over-dose begs belief ?!!
     
  12. scanjock8

    scanjock8 Active Member

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    i was diagnosed with clinical depression about two years ago and began regular therapy combined with taking wellbutrin. luckily, i did not have to try different medications before finding one that suited me, and i've experienced no adverse side-effects (in fact, they've been pretty positive--no loss of sex drive whatsoever, lost a few pounds, more energy and even greater clarity of thought). but i'm told i do not have anxiety with depression, which makes me a candidate for this type of drug.

    of course the meds, regardless of variety, should be combined with some form of licensed psychotherapy for most people. i'm always amazed at the number of people i know that get antidepressant prescriptions from other doctors like their gp or ob/gyn, yet never see a psychiatrist.
     
  13. D_electric chair

    D_electric chair New Member

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    I havent take it for about 6 months now. Im not suicidal though. I think life is worth more and the greatest thing to happen. And sex side affect, another reason why I wouldnt use it. I just want to live a happy life and have a smile on my face and not think about the bad shit.
    Thank guys/gals
     
  14. Heather LouAnna

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    lol Your user name suggests otherwise. Good luck.
     
  15. jeff black

    jeff black <img border="0" src="/images/badges/gold_member.gi

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    Seriously, man. TAKE THE pills!! Just stick it out for 2 months.. and then, if you dont' want to continue.. don't.. but at least give them a chance to succeed. Even if u are not thinking of suicide, the thoughts can come up.
     
  16. chrisung

    chrisung New Member

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    Very seriously man - don't listen to us yoyos on the internet. Talk to your DOCTOR.

    What works for my depression doesn't work for anyone else I know. It took me two years to get on the right stuff (much of it worked, but had bad side effects), but the journey was worth it. Everyone on an antidepressent in my life is on a different one or differrent dosage. Our doctors helped sort us out.

    There's no way in hell I would trust my life and health in a medical matter to us annonymous (or semi-annonymous) people wandering around here. However good intentioned we are (and I honestly think everyone in this thread is well intentioned), we don't know your complete history or other stuff going on in your life.

    Use us for sounding board. Use us for asking our experiences. Don't use us as a substitute professional.

    Talk to your doctor. They are the one most qualified and able to help you.
     
  17. dkmilker

    dkmilker Member

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    [quote - Scanjock8] of course the meds, regardless of variety, should be combined with some form of licensed psychotherapy for most people. i'm always amazed at the number of people i know that get antidepressant prescriptions from other doctors like their gp or ob/gyn, yet never see a psychiatrist.[/quote]

    This was my concern as well. I may have missed something, but it is not clear to me exactly what you were taking the Zoloft for. Depression? Anxiety? Compulsive preoccupations? As mentioned before, you need to talk to your doctor. If you posted this thread because you were dissatisfied with the answers your doctor gave you, then you should request a referral to a different doctor. Whomever prescribed this medication to you should have discussed the side effects and estimated time of the relief of symptoms. You shouldn't have to go online to get this information after the fact. It should have been in your hand before you went to the pharmacy.

    I suspect you are not getting the proper medical attention you deserve. I don't think it's a good idea to seek specific medical advise online. You should talk face to face with a medical professional and, if you are told that you need medication, try to get prescriptions only from specialists, if at all possible.
     
  18. DC_DEEP

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    Those who advocate going ahead and taking the pills, regardless of the side effects, I agree, somewhat. It depends upon how severe the side effects are.

    There is a common misconception that when you start taking antidepressants, the results are immediate. They do not function as other drugs do. You don't take one dose, and 30 minutes later feel as though you are on top of the world. I don't know of any antidepressants that do not have to do a process of protein-binding in the bloodstream and neurotransmitter regulating. This usually takes (as mentioned before) about 2 to 6 weeks.

    Most often, over this 2 - 6 week period, minor side effects will lessen and then stop as your body adjusts to it new "balance of chemistries." If you are having just some annoying nausea, stick it out until you can adjust, and stick to your dosing schedule very strictly.

    If, on the other hand, your symptoms are severe, (vomiting with the nausea), dizziness to the degree that you cannot keep your balance, others... call your doctor immediately and discuss the problem. Chances are, he will change your dosage or more likely, try another product. Don't give up.
     
  19. B_Stronzo

    B_Stronzo New Member

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    RazorSharp?

    I had a short unhappy experience with that drug.

    A psychopharmacologist put me on it in Boston when it first was approved. I spent two weeks staring at the kitchen ceiling. When my boyfriend finally called the doctor and said "Stronzo seems to have checked out" my psychopharmacologist said "tell him to stop taking it at once!"

    For me it was like being on a bad acid trip (not that I'd know mind you):rolleyes:
     
  20. DC_DEEP

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    And people wonder why I rant so often about experimenting with various kinds of drugs. I worked for several years in The Department of Pharmaceutical Sciences in a medical school, so I've seen a great deal of the education and research that goes on. Psychotropic drugs and hormones aren't like taking aspirin. They can save lives, but they can also destroy them if not used properly.

    I'm glad you had some support there, Stronzo. People often don't realize that changes in your blood chemistry can change your personality and perceptions. Neurotransmitter imbalances are not simple or casual. You probably either 1) had no perception of staring at the ceiling, or 2) realized what was going on and thought "this is scary, its' not like me", or felt like you were watching yourself from across the room but were unable to react.
     
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