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It's ok, I'm not offended or taking anything personally when we discuss things. I hope you feel the same way.
I'm just going by statements made by the other organizations which put the effectiveness as low as 92 percent.
I'm don't think it's disingenuous to question study methodology. I am basically agreeing with you.
People lie, they say they take PrEP consistently and don't. Their positive results contaminate the data. So basically I was leaving the door open to an effectiveness higher than low 90s. Your examples of ruling out outliers is essentially an example of questioning the data as well.
K. The caveat is always you need to take the treatment correctly in order to for it to work. Clinical trials don't put the data from those who didn't follow the protocol in effectiveness. PrEP is 99.99% effective if you take the damn shit.
If you don't... then it don't work. Let me explain how the controls on this study work. They gave the drugs to patients DAILY. They took bloods frequently to measure the levels of the meds. The reliability of the data is impeccable. The study was conducted this way precisely for reasons you raise. No one not taking their meds nor lying was included in the data. That is such a serious charge of academic misconduct it is almost criminal. I would very much like to see where this info you are citing is from. It's nonsensical.