Both vaccines are given as shots and require 3 doses.
How are the two HPV vaccines different?
Only one of the vaccines (Gardasil) protects against HPV types 6 and 11, the types that cause most genital warts in females and males.
Only one of the vaccines (Gardasil) has been tested and licensed for use in males.
While both vaccines protect against HPV16, which is the most common HPV type responsible for HPV associated cancers including cancers of cervix, vulva, vagina, penis, and anus and oropharynx, only one of the vaccines (Gardasil) has been tested and shown to protect against precancers of the vulva, vagina, and anus.
The vaccines have different adjuvants—a substance that is added to the vaccine to increase the body's immune response.