After my vasectomy I had a few complications. When I went back to the urologist he told me that the size of my testicles and they way my scrotum hung meant I needed more support during the healing process and I needed to wear a tight jock strap for awhile. I didn't take it as a compliment, but the advice did help.
As far as comments from women, I've had a few, but they are less frequent than cock comments. My take is that some women really do have additional interest in balls (where a large number seem to find the scrotum / balls somewhat gross). I had one women who always wanted me to "get my cock out of the way" so she could see my balls hang between my legs. Better yet she loved to sit underneath me while I stood with my legs apart and lick and suck my balls and sack. She really wouldn't give head though. Odd.