Though my experience with women is sorta limited, I don't think there's a big difference when it comes to fucking someone.
One of the things I've learned is that it's easiest to penetrate (after lots and lots of foreplay) if you're only about half- or three-quarters up. Trying to cram a fully erect large penis into an unprepared hole is difficult for both parties. But inserting something neither as fearsomely large nor as painfully hard is actually easier, and there's the added sensual bonus of getting bigger (and harder) as you go.
Trust me on this: it works.