There are actors who were on the show and managed to get big gigs later on. Beyond the names people already threw out, Eka Darville (Power Rangers RPM) was on Spartacus and later got one of the lead roles on Jessica Jones for 3 seasons on Netflix and a lead on Tell me a Story's second season last year.
There are more of course but most of the cast went into obscurity - which isn't exactly surprising as as most young actors aren't exactly becoming big names later on.
A lot of them are not even actors and they are recruited via martial arts circuits (Danny Slavin being one example mentioned above).
So the show isn't really a "death sentence" but it's not exactly a "jumping point" either.
And to keep with the thread's topic, since we talked about Eka Darville, here is his wonderful physique from Jessica jones