There have been several threads on this forum about low libido, low testosterone, and testosterone replacement therapy. As I stated in those threads, my libido went away about 2.5 years ago (approx. July 2006). At first I thought it was stress. After that stressful period ended, I waited patiently for my libido to come back. It didn't. Finally, in Spring 2007, I told my doctor what was going on. He checked my testosterone level (355) and declared them normal. I kept complaining, and about a year later, he tested my levels again (304) and referred me to an endocrinologist. It tooks months to get an appointment to see the endocrinologist. After 3 appointments and lots of tests (testosterone, estrogen, estradiol, cortisol, ACTH, growth hormone, etc., etc.) he declared everything to be normal and sent me back to my regular physician. This time the blood samples were drawn at 7:30 a.m., when hormone levels are at their highest. (Previously they had been drawn late morning/early afternoon.) This time, my testosterone was 460. Today I saw my new regular physician. (My old physician left the practice.) My new physician is a gay man who is a specialist in men's health and gay health issues, has a background in psychiatry, and formerly taught at Harvard Medical School. He disagreed with the endocrinologist and said that my T levels are quite low for a man my age. He essentially agreed with what Dave NoCal said in this post... http://www.lpsg.org/57168-young-low-libido-has-happen.html#post941715 ...that having a T level within the normal range, which is quite broad, doesn't mean that they are normal for ME. He said if a man has symptoms of low testosterone, he probably has low testosterone (for him) and that if we had a record of my T levels before my libido went away, they would probably have been a lot higher than what they are now; what is normal for me could be as high at 800 or 900. So I start testosterone replacement therapy tomorrow. I'm hopeful yet cautious. I want the TRT to work, but I'm worried that it won't.