Thanks, Hung in DC, for sharing this information. Some additional information:
MPOX (the better way to refer to 'monkeypox') can be spread even if those involved are wearing condoms. Skin to skin contact (skin anywhere on the body) for prolonged periods is the primary way it is spread.
The vaccine being distributed now is actually a modern smallpox vaccine. It was NOT designed specifically for mpox.
A limited study done some time ago indicated that smallpox vaccines are only about 85% protective against mpox. I am sure there will be 'breakthrough' infections following vaccination efforts, so keep up on health news for more accurate data as it becomes available.
If you were vaccinated against smallpox as a child (back before 1972, when smallpox was considered eradicated and routine vaccination was stopped), it is unlikely that your smallpox vaccination would provide much protection against mpox today. Therefore, you should get BOTH shots. However, if you were in the military and were given a smallpox vaccine more recently, you probably have some protection.
Peak protection from the vaccine is 2 weeks after the SECOND vaccination.
About 40% of today's mpox infections have been in men who were HIV+. It is unclear whether that means that HIV-infection makes someone more vulnerable to infection.
The administration of the vaccine was originally subcutaneous. However, it has been shown that using only 1/5th of the dose administered intradermally (into the fat layer of the skin) provides a similar immune response. This route of administration stretches supplies considerably. HOWEVER, for people who develop keloids, it should be administered subcutaneously to prevent scarring. In addition, those who have t-cells below 300 (immuno-compromised HIV+ individuals primarily) should also receive the shot subcutaneously.
The vaccine can be therapeutically useful to lesson symptoms for people who have been exposed to mpox or those who are starting to show signs.
The antiviral treatment TPOXX (tecovirimat), an investigational drug, is available for mpox infections. It was originally designed for smallpox infections but, so far, its access is being limited to the most severe cases and there is a tremendous amount of paperwork in order to gain access to the treatment.
If you feel you are at risk for mpox and are HIV-, PLEASE consider getting tested for HIV and talk to your healthcare provider about going on PrEP to protect against HIV!
I hope this is helpful. I got my first vaccination on August 1 and look forward to a booster as early as next week. There have been 30 cases so far in Sonoma County, California as of yesterday.