NO2 and erections

getnbiggrTO

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Hey all,

a quick question about the bodybuilding supplement Nitric Oxide -- ie NO2. A friend of mine has reported stronger, bigger, harder erections from taking it, and given that it's billed as a "hemodilator" that is supposed to increase blood flow, that makes sense.

That being said, there's a lot of snake-oil out there in the supplement business. So I was wondering if anyone here has had experience with NO2 -- were the sexual side-effects all they're cracked up to be? were there any useful bodybuilding effects? and were there any negative side-effects?

-- J.
 

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Nitric oxide is NO, not NO2, which is nitrogen dioxide, a red-brown gas and nasty stuff, reacting with water in your body to form nitric acid. Nitric oxide, which is a colourless gas, will react with oxygen to form nitrogen dioxide, so it's not safe to take either. It is a vasodilator, meaning it dilates blood vessels, formed in the body at the points where it's needed, including to produce erection. Presumably this "supplement" is something else?
 

fri2219

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NO is a neurotransmitter. If you're looking for side effects from abuse, use your imagination and think of what happens when people abuse drugs that affect neurotransmitters, like meth, cocaine, Paxil, etc...

In addition to being a neurotransmitter, NO affects the same systems of regulation that drugs like cialis and viagra target- if you take NO at the same time you take one of those PDE-5 inhibitors or other classes of drugs like [SIZE=-1]Angiotensin-converting Enzyme[/SIZE] or [SIZE=-1]monoamine oxidase-B inhibitor[/SIZE]s, you stand a decent chance of killing yourself.

If you want a little light reading on the subject, visit the National Library of Medicine and use the bold words for search terms on Medline: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi
 

DC_DEEP

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fri2219 said:
...
In addition to being a neurotransmitter, NO affects the same systems of regulation that drugs like cialis and viagra target- if you take NO at the same time you take one of those PDE-5 inhibitors or other classes of drugs like [SIZE=-1]Angiotensin-converting Enzyme[/SIZE] or [SIZE=-1]monoamine oxidase-B inhibitor[/SIZE]s, you stand a decent chance of killing yourself...
fri2219, thanks for pointing this out. In several other threads, I have tried to point out that recreational use of prescription, OTC, or street drugs can be very dangerous. Blood chemistry is very complex and very delicately balanced. In the normal body, with no dysfunction, it's easy to really screw things up. Even slight changes can cause major problems, and most chemicals have effects on more than one body system. That's why even the tested and regulated prescription drugs almost always have undesirable side effects. Even something as simple as taking tylenol for a hangover headache causes toxic reactions in the body, and wreaks havoc on the liver. If you feel you absolutely MUST take recreational drugs, at least do a little research to find out what they are and how they affect your body.
 

getnbiggrTO

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Ope - guess I should have done some more reading/investigating before I posted. Didn't mean to cause such consternation.

What in fact I was asking about was legal, over-the-counter nutritional supplements like "N.O. Explode" containing
L-arginine, L-tyrosine, taurine, etc. which are purported promote the body's own production of Nitric Oxide, among other things. More detail on this particular product can be found here: Bodybuilding.com - BSN NO-Xplode - Extreme Nitric Oxide & Creatine Surge! On sale now!

At any rate, the reason I asked is b/c of the ways in which the "nutritional supplement" industry is seemingly under-regulated, which leads to a lot of bogus claims. But a friend who had taken this product had reported extra-strong erections as a side-effect, which sounded interesting, and so I was just looking for some discussion on it...
 

moishglukovsky

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NO is nitric oxide. It's a key signaling molecule in the body. The elucidation of the biochemistry of its mechanism won the Nobel Prize in 1998.

NO is a vasodilator -- opens up blood vessels to allow better flow.

It is used in VERY LOW concentrations (parts per million in air) to treat neonatal pulmonary hypertension ("blue babies"). This product is regulated as a drug.

NO's effects are seen in drugs like Viagra (which produces/encourages production) of NO in the human system. Nitroglycerine for angina works by the same mechanism of releasing small amounts of NO into the system for vasodilation.
 

D_Herin_Ghan

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I take NO-Xplode, if you get an erection within an hour of taking the stuff (which happened to me when my girlfriend surprised me before I left for the gym), your erection is definatley fuller, longer and harder. However, I see no effect if you take it, work out for a while and then get one. The stuff does wear off after a bit.

I'm beginning to stack with Nitrix effective next week, but so far the only side effects for me have been increased mass, concentration, and pumps.