Im a 33yo gay male, have been using poppers during sex, I'd say about 70% of the time, since I started having sex with men when I was 21. About 4 months ago, I realized there was a perforation (hole) in my Septum, (the wall between your nostrils) I just about fainted. Went to all the appropriate Docs, with gazilion tests run, and nothing came back positive. We just wrote it off as a fluke related to my deviated septum. Could inhaling poppers have caused this? What are the effects that poppers could have on your Septum? Could prolonged use cause a perforation (hole) in your Septum? Anyone's thoughts or experiences with an issue like this would be GREATLY appreciated. I am getting my nose fixed, but if poppers could have caused this, there is NO WAY I'll ever pick up a bottle of poppers again. Thanks.