Wall Street Journal: A HIV patient now "functionally cured" after bone marrow transpl

Discussion in 'The Healthy Penis' started by jamesdarlington, Nov 11, 2008.

  1. jamesdarlington

    jamesdarlington New Member

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    Apparently a HIV infected person who also had lukemia recieved a bone marrow transplant to treat his lukemia and "appears to have won his battle with AIDS."

    To make a long story short : In the treatment of lukemia doctors completely destroy your bone marrow cells by blasting them with radiation and chemtherapy, to ensure that all the cells are dead, so that no cancer can return. Bone Marrow cells are the cells that produce your white blood cells, your white blood cells ARE your immune system.

    Once they killed of all the canceros (lukemia) bone marrow cells, they replaced them with the bone marrow cells from a donor who is naturally immune to HIV. And now that the HIV infected patient has bone marrow that produces white blood cells that are immune to HIV, he now has an immune system that is immune to HIV. Doctors have not detected HIV in his blood for over 600 days, even though he stopped taking all of his HIV meds since the marrow transplant. The doctors are saying that he is "functionally cured".

    Now before you guys go out there and start having sex without using a condom because you think this is the cure for aids, keep this in mind. 30% of bone marrow transplants are fatal and some people are required to take immonosuppresant medication everyday for the rest of their lives to keep their immune system from killing the donor marrow. Having to take immonosuppresants is like having aids.

    Here is the link A Doctor, a Mutation and a Potential Cure for AIDS - WSJ.com

     
  2. cityboy

    cityboy Member

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    Wait!
    So they completely destroy your cancerous bone marrow so that you have no immune system.

    So they replace immune system with a donor immune system that functions correctly? Right?

    What? I thought you said they destroyed the original immune system and replaced it. If it was destroyed how come they have to take meds to keep a now supposedly now non-existent immune system from destroying what it was replaced with?
     
  3. kabutops74

    kabutops74 New Member

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    I'm not a biologist, but I think there's more to the immune system than white blood cells -- which were the only things specifically mentioned as deriving from bone marrow. So the immunosuppressants would be to keep the native immune system from flipping out over the new neighbors, as with many transplants.
     
  4. jamesdarlington

    jamesdarlington New Member

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    Because sometimes the "new" donor immune system cells will start attacking the recepients tissue. In other words, the new white blood cells will think that everything around them, in this new body, is a foreign invader and they will start destroying it.

    If this happens they will eat away at the major organs and kill the person if they do not take immunosuppresants.
     
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