Xiaflex

bigdex

1st Like
Joined
Jan 12, 2010
Posts
133
Media
1
Likes
1
Points
103
Location
ireland
Sexuality
100% Straight, 0% Gay
Gender
Male
This could be the future for chemical PE. It weakens collagen.

https://www.xiaflex.com/

At the bottom it warns that it can weaken ligaments. A low dose injection into the suspensory ligament might help it to stretch. An injection into the tunica may help it to stretch for increases in lenght and/or girth. Would be risky though.
 

Big Al

Sexy Member
Joined
Jul 1, 2008
Posts
2,725
Media
0
Likes
47
Points
123
Sexuality
No Response
Gender
Male
This could be the future for chemical PE. It weakens collagen.

https://www.xiaflex.com/

At the bottom it warns that it can weaken ligaments. A low dose injection into the suspensory ligament might help it to stretch. An injection into the tunica may help it to stretch for increases in lenght and/or girth. Would be risky though.

The PC, suspensory lig, and fascia are actually a "superorgan" in that they all connect together. A truly fit penis should have flexible and strong ligaments.
 

Big Al

Sexy Member
Joined
Jul 1, 2008
Posts
2,725
Media
0
Likes
47
Points
123
Sexuality
No Response
Gender
Male
so Big Al is this a good thang or bad

From my viewpoint, it's "bad". Sacrificing ligament strength and health for the possibility of extra size isn't a good trade off. Also, even with weakens ligs you'll STILL likely need to do some form of stretching. How your penis will react to that after being weakened remains to be seen.
 

bigdex

1st Like
Joined
Jan 12, 2010
Posts
133
Media
1
Likes
1
Points
103
Location
ireland
Sexuality
100% Straight, 0% Gay
Gender
Male
There is an enzyme that breaks the collagen crosslinkage but I don't think that xiaflex does that. Therefore, it probably won't be a good idea to take it for PE.

To bigal you could take something that weakens the penis and helps you enlarge it and then strengthen it once you have reached your desired size. I think most exercises increase collagen production that is why it gets harder to gain the longer you are at PE.
 

Big Al

Sexy Member
Joined
Jul 1, 2008
Posts
2,725
Media
0
Likes
47
Points
123
Sexuality
No Response
Gender
Male
There is an enzyme that breaks the collagen crosslinkage but I don't think that xiaflex does that. Therefore, it probably won't be a good idea to take it for PE.

To bigal you could take something that weakens the penis and helps you enlarge it and then strengthen it once you have reached your desired size. I think most exercises increase collagen production that is why it gets harder to gain the longer you are at PE.

Collagen isn't the enemy- connective tissues are composed of it. I think there may be some confusing of collagen with "scar tissue". If there were a build up of scar tissue then you'd see injuries like Peyronie's and, at the very least, a decline in performance.

As for why it gets harder the longer you do PE, it's the law of diminishing returns.

I should note that by injecting the area of the pubic base you'll not only be affecting the penis, but you could also affect surrounding structures like the pelvic floor- which are all "connected" in that they work together to do much more than maintain the stability of the penis.
 

bigdex

1st Like
Joined
Jan 12, 2010
Posts
133
Media
1
Likes
1
Points
103
Location
ireland
Sexuality
100% Straight, 0% Gay
Gender
Male
I disagree. In cases where priapism resulted in megalophallus the conclusion was that the priapism resulted in permanent lose of elasticity of the tunica. Scar tissue is just a build up of typeI collagen. I think that PE results in the build up of typeI collagen thus reducing gains in the long term. Collagen can reform over time which is why taking breaks helps with PE IMO.
 

Big Al

Sexy Member
Joined
Jul 1, 2008
Posts
2,725
Media
0
Likes
47
Points
123
Sexuality
No Response
Gender
Male
I disagree. In cases where priapism resulted in megalophallus the conclusion was that the priapism resulted in permanent lose of elasticity of the tunica. Scar tissue is just a build up of typeI collagen.

I think that PE results in the build up of typeI collagen thus reducing gains in the long term. Collagen can reform over time which is why taking breaks helps with PE IMO.

Scar tissue [which is composed of Type I collagen] build up would restrict erections/gains because in the penis because it would induce Peyronies- which is essentially defined as "...a fibrous inelastic scar involving the tunica albuginea of the corpora cavernosa".

You do bring up an interesting case though- re: megalophallus.

Priapism very rarely results in megalophallus- most often (if left untreated) it results in tissue death and/or Peyronie's. That's one of the reasons why when the clips became popular on the various forums that I distinctly advised men not to try to purposefully cause priapism in an attempt to induce "megalophallus". To my horror, not too long after the article spread some men were attempting to do just that very thing :(

A sudden expansion of the tunica resulting in permanent distortion can be explained by what occurs during mechanical creep- though mechanical creep is often performed mush more slowly. There's even formulae for *estimating strain-time relations effect's on the degree of tissue expansion.

Training breaks are helpful for several reasons. Most systems of progressive resistance seem to work best when performed in an upward trending but cyclical manner. This allows for full healing and it also has a distinct effect on the mental aspect of training. A decline in EQ or a lack of gains due to overtraining is not the same as a build up of scar tissue though.

In the case of Peyronie's, it's estimated that about half of all sufferers actually get worsening symptoms over time. This figure does not take into account men doing any kind of PE- it actually encompasses men not doing anything at all to treat these symptoms (similar to what would occur during a break in training).

* Non-linear strain-time relations don't always fit within these models.
 

bigdex

1st Like
Joined
Jan 12, 2010
Posts
133
Media
1
Likes
1
Points
103
Location
ireland
Sexuality
100% Straight, 0% Gay
Gender
Male
Pentox and viagra have been used to treat peyronies and megalophallus. They prevented fibrosis. I'm thinking of trying to induce priapism while taking pentox. I will also be doing exercises during the priapism to help move fresh blood in and stale blood out ( jelqing and reverse jelqing). Am I crazy?

I think that a priapism induced megalophallus is time dependent (I have no evidence for this it's just my theory). Let me explain. Ronielle the guy who's been giving himself 3 hour erections has only seen a 2 inch gain in around 2 or 3 years. He gives himself around 3 of these mini erections a week. I think that the time isn't sufficient to stretch beyond normal limits and produce a permanent lose of elasticity in the tunica. I'm thinking of going for a 8 maybe 12 hour priapism while at the same time doing everything to minimize fibrosis.

ED is not permanent. An experiment where participants were given viagra every night for a year found that they were cured of ED. The control were given viagra to take when needed. The control saw no improvement in erectile function.

I'm thinking that if I do give myself ED I could take viagra for a year and reverse the damage. Crazy I know. I'm still in 2 minds if i will go ahead with this.
 

Big Al

Sexy Member
Joined
Jul 1, 2008
Posts
2,725
Media
0
Likes
47
Points
123
Sexuality
No Response
Gender
Male
Pentox and viagra have been used to treat peyronies and megalophallus. They prevented fibrosis. I'm thinking of trying to induce priapism while taking pentox. I will also be doing exercises during the priapism to help move fresh blood in and stale blood out ( jelqing and reverse jelqing). Am I crazy?

I think that a priapism induced megalophallus is time dependent (I have no evidence for this it's just my theory). Let me explain. Ronielle the guy who's been giving himself 3 hour erections has only seen a 2 inch gain in around 2 or 3 years. He gives himself around 3 of these mini erections a week. I think that the time isn't sufficient to stretch beyond normal limits and produce a permanent lose of elasticity in the tunica. I'm thinking of going for a 8 maybe 12 hour priapism while at the same time doing everything to minimize fibrosis.

What type of contingency plans do you have for reversing this process- in case of emergency? While exercise may be effective at keeping blood flow circulating, there's still a possibility of tissue exhaustion (especially if you're not accustomed to holding erections for that long a period). While I wouldn't recommend what you're doing, perhaps a graduated approach to increasing erection times will yield results with less risk(?)

ED is not permanent. An experiment where participants were given viagra every night for a year found that they were cured of ED. The control were given viagra to take when needed. The control saw no improvement in erectile function.

I'm thinking that if I do give myself ED I could take viagra for a year and reverse the damage. Crazy I know. I'm still in 2 minds if i will go ahead with this.

"ED" is a generic term and can encompass organic problems that may require surgical intervention or outside stimuli in order to induce/improve erections. Viagra has helped a lot of men, and using it (or another type of erector) in conjunction with exercises would yield better results than taking the drug alone.

While it's not anything that I'd personally recommend, I do understand that breakthroughs are often made by crossing boundaries- even dangerous ones. Whatever you decide to do- there's a growing interest in chemical experimentation with PE, and it would be most appreciated if you could share your experiences with us. Please use extreme caution in your endeavors though- you only have one penis.
 

hsarge

Sexy Member
Joined
Nov 5, 2009
Posts
1,184
Media
0
Likes
36
Points
73
Location
PA
Sexuality
100% Straight, 0% Gay
Gender
Male
Bigdex, maybe you don't know that Big Al is 'Al' Alfano probably the foremost PE expert who contributes to this site. You should read his articles and posts at other sites before you so curtly dismiss his advice. Just because 'ignorance is bliss' doesn't mean it is safe.
 

bigdex

1st Like
Joined
Jan 12, 2010
Posts
133
Media
1
Likes
1
Points
103
Location
ireland
Sexuality
100% Straight, 0% Gay
Gender
Male
Trust me hsarge I highly respect the opinion of BigAl. I am having doubts about whether I should do this experiment. I am not ignorant. I have read about cases where people have had priapisms and they didn't suffer ED and this is what I'm trying to emulate. Under normal conditions an extended priapism will lead to ED but there has been cases where treatment with pentoxifylline and viagra have pevented this from happening.

The thing is I've developed a great rountine which I'm seeing great results. I'm taking 25mg of viagra every night which I think is helping great also. I've order enough viagra and pentox to do me 6 months. I'm thinking I might just save my money and stick to the viagra and pentox.

I do believe that the reason why no one has been able to emulate the condition of megalophallus through chemically induced priapism (at least in the short term) is due to the duration of the priapisms. I think that the time under tension due to a priapism will give exponential results i.e. double the time may give 3 or 4 times the results. This would mean that only a few long duration priapisms would need to be experienced rather than hundreds of short ones.

Ronielle has seen a gain of 2 inch in length and 1.5 in girth but he has been following a chemical routine for 30 months. Fuck that. I can achieve that with natural penis enlargement techniques.

Chemical PE is the future. It will one day replace the surgery that has left so many men disappointed and disfigured. The dissatisfaction rate with surgery is greater than 50%. Most men, can't stick with PE long enough to see good results.

However, I'm not sure if this is right for me. After a PE session my girth is sometimes around 6.5 or 7 inches. These figures will probably be my permanent girth in the next few months. If I was to try this experiment I could end up with too much girth.
 

hsarge

Sexy Member
Joined
Nov 5, 2009
Posts
1,184
Media
0
Likes
36
Points
73
Location
PA
Sexuality
100% Straight, 0% Gay
Gender
Male
Buffed, no rebuff intended. Two questions for you:

1) what is you definition of a prolonged erection and priapism?

2) have you had any side effects from daily prolonged use of Viagra, and did such side effects (headache, visual sensitivity, etc) lessen with time?

Thanks.
 

bigdex

1st Like
Joined
Jan 12, 2010
Posts
133
Media
1
Likes
1
Points
103
Location
ireland
Sexuality
100% Straight, 0% Gay
Gender
Male
The only side effect that I have noticed is being a little bit light headed in the morning but nothing severe. No visual sides and no lessening of effect. I have started to avoid eating after 6 oclock and take my viagra just before I go to bed. Food really dampens the effect of viagra.