... Someone at our uni recently died, one of his friends friends to be exact, from an ecstasy overdose - at that point we all assumed he would stop instantly - but he didn't. I know ecstasy in small doses isn't really that dangerous, well or so I thought.
He's admitted to me know that although he's not addicted, he no longer really enjoys nights out when he isn't on it. And whereas before he'd only do it at a certain club known for drugs with a group of people with everyone on it, he now has started taking it at normal clubs when he goes out with none-users and lies about using it.
Coincidentally, around the time he started using it he has started to lose weight, lose his appetite, when he does eat he feels sick.
His usage isn't out of control yet, it's once every week or so, which doesn't explain his sudden weight loss as it's only a temporary appetite suppressant, and no one else in our group of friends who uses it has lost any weight - is this a side effect of it?
I've told him I don't like it and he isn't allowed to see me whilst he's high, or for a few days after because the taste makes me gag, I don't want to be the controlling boyfriend who tells him to stop taking it as I don't think anyone really has the right to tell anyone to stop taking a certain drug, but I'm just worried for his health.
Does anyone on here have any experience with MDMA, is it linked to long-term weight loss? Any other side effects I should look out for?
Thanks x
Seems like you need some decent info on XTC (there's a lot of "info" out there on the internet, but not all trustworthy), I had a course on toxicology last year in which the subject came up, so I quickly reread it and rougly summarize some known/scientific facts:
(my own comments I added in italic)
- it was developed as a medical drug in 1914 by Merck as an
appetite suppressant (which would explain why he lost weight and doesn't eat as he used to)
- one pill usually contains 75-150 mg MDMA
(note the big difference in dosage, not all XTC is the same!)
- in 1950 the american army studied it as a neurotoxic agent and in 1970 they used it during psychotherapy (it's an entactogenic drug
(inducing feelings and empathy, opening up the mind) and proven to be an effective treatment for post-traumatic stress syndrom). Since then it's made it's way to being used for recreational purposes (parties).
- farmacokinetics: the effects kick in after 30 minutes and last on average 4-6 hours
- effects: it releases serotonine in the brain nerve endings, it blocks serotonine reuptake and prevents
(permanently! - effect lasts 1 week) serotonine degradation. This permanent inhibition of the degradation of serotinine happens by blocking an enzyme (tryptophan hydroxylase, for the science geeks ^^ ?correct translation) which has a turn-over (= rate the enzyme is produced) of about one week)
(this is a possible explanation of why your bf would only take about one pill a week - if he takes one sooner, it wouldn't have the same (full) effect)
This higher serotonine concentration in the brain generally gives a feeling of well-being, there's a higher need of company and social interactions are much smoother
(people want to get cozy). They can feel euphoric or act reckless, loss of inhibitions. The pupil of they eye dilates, heart rate rises, body temperature rises. There can also be shaking, teeth grinding, muscle cramping and restlessness (they typically can't fall asleep). These effects are very divers and can be different for everyone, but that's the general scope.
After those 4-6 hours, the person will feel tired and depressed due to the serotonine depletion. Often they take a new pill to delay these effects, further depleting their serotonine storage levels.
-
! even a normal dose can cause myocardial infarction and fatal heart rythms, a person that dies from XTC did NOT necessarily overdose! There's been numerous reports in scientifical articles. A cardiac predisposition (for example when cardiac diseases run in the family) will up this chance but isn't essential. Every one of those cases was also combined with an extreme body temperature of T>40°C.
(Note that this does not happen often, but there is a possibility. It's not my intention to scare people mentioning this, but I think it's important you're informed.)
-
Chronical use results often in depression, paranoia, liver diseases (jaundice), troubles with jaw muscles and toxic neuropathy
(lasting shortage of serotonine in the brain - the serotonine receptors in the brain are degenerated).
- The illegal production of XTC is easy, but also results in a teratogene (causes malformation of a fetus) substance, safrole. Since it's illegal, and purifying XTC is not very high on the drug dealers to-do list (it's costly)... you can do the math. Pregnant woman should never take XTC.
So far what was in the course. I definitely think there's a reason that XTC is illegal... (at least in Belgium).
...and no one else in our group of friends who uses it has lost any weight - is this a side effect of it?
This might be a sign that the others do not use it as much. He lies to others about using it, I would consider the fact that he might lie to you about it, as well.
He's admitted to me know that although he's not addicted, he no longer really enjoys nights out when he isn't on it. And whereas before he'd only do it at a certain club known for drugs with a group of people with everyone on it, he now has started taking it at normal clubs when he goes out with none-users and lies about using it.
This is a tell-tale sign of addiction.
I'm sorry you have to deal with this situation. You're right, if you're the one trying to prevent him taking XTC, you're "the bad guy", and it should be his own choice no matter what.
I'm afraid it's only going to get worse though. I would tell him what I know about the drug, and let it rest. Big chance that he's not informed about it as he should be. Big chance that he doesn't want to be either...
I hope you get through this, together. But battling an addiction is one of the hardest things, and chances are you will be the one who ends up hurt. Thread carefully. Prepare to walk away if you have to. Addiction is self-destruction, and it is hardest on the ones who love the addict... Good luck, stay strong. I really hope everything turns out okay for you.