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34273891

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Good afternoon, everyone. I have been on semaglutide for about nine months, and am quitting it entirely; today is my final dose, after tapering off for several weeks. After losing thirty pounds, I have plateaued. I am not diabetic, which has been somewhat problematic, for two reasons:

1) Semaglutide drastically lowers your blood sugar levels; mine were always relatively normal.
2) It is very difficult to secure a prescription that Insurance will cover, without a diabetes diagnosis.

Previously, I was on a hybrid form of the ketogenic diet. In the Summer of 2022, I weighed approximately 400 pounds. I currently weigh +/- 285 pounds, which is the lightest number I have been in recent years. The smallest I ever was in my adult life was around 245. Even for a six-foot tall man, that is quite heavy; certainly not husky, just plain fat.

I am encouraged by my success and ongoing ability to lose weight. Semaglutide has certainly played a small part in that. However, not being on it anymore, I am concerned about gaining some of the weight back. So far, so good (no weight gain, yet), but I have no illusions, and I am well aware of the risks and dangers ahead.

For those of you who have gone through similar trials, what have you found to be efficacious after quitting semaglutide? I have a host of other issues, but they are currently in check, functionally speaking. All that needs to be addressed now are my ongoing dietary and exercise-based initiatives. I believe that going back onto a ketogenic-like diet will be rather beneficial, for the time being. It's not a permanent solution, but it worked very well before, and I believe my body is ready to do it again, for a time.

Here are some of the negative side effects of being on semaglutide:

1) Stomach upset and nausea.
2) Intolerance to alcohol.
3) The sensation of feeling full is somewhat delayed; one could eat too much and not even know it, causing problems, later.
4) Low Blood Sugar; this results in a lack of energy, at times, and further causes alarming instances of light-headedness.
5) Intolerance to sugar alcohols.
6) Intolerance to spicy foods.

In the end, I don't recommend it for those whose primary goal is weight loss. I make no comment to patients with diabetes; that is a separate issue, entirely. In any case, I recommend you speak with your Physician, and follow his/ her expert medical advice.
 
Congrats on the massive weight loss — 115 pounds is no joke.

In the US Semaglutide has been approved for weight loss in addition to diabetes.

Have you actually experienced all of the negative side effects? Or are you just listing them?

2) Intolerance to alcohol.
5) Intolerance to sugar alcohols.

I wouldn't describe it as an intolerance but rather a lack of desire to consume it, which is hardly a negative side effect.

6) Intolerance to spicy foods.

I haven't heard of this negative side effect. I think it's just similar to alcohol in that if you already have a sensitive or upset stomach you shouldn't consume it.

what have you found to be efficacious after quitting semaglutide?

You can try Berberine which is considered to be a natural alternative.

I don't recommend it for those whose primary goal is weight loss.

Semaglutide is just another tool in the toolbox for weight loss and diabetes maintenance.

It doesn't work for everyone but some people, such as myself, don't experience any side effects.

I think it really boils down to the root cause of weight management issues. If it's because of hormonal, addiction or psychological issues then semaglutide can't fix that.
 
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Congrats on the massive weight loss — 115 pounds is no joke.

In the US Semaglutide has been approved for weight loss in addition to diabetes.

Have you actually experienced all of the negative side effects? Or are you just listing them?




I wouldn't describe it as an intolerance but rather a lack of desire to consume it, which is hardly a negative side effect.



I haven't heard of this negative side effect. I think it's just similar to alcohol in that if you already have a sensitive or upset stomach you shouldn't consume it.



You can try Berberine which is considered to be a natural alternative.



Semaglutide is just another tool in the toolbox for weight loss and diabetes maintenance.

It doesn't work for everyone but some people, such as myself, don't experience any side effects.

I think it really boils down to the root cause of weight management issues. If it's because of hormonal, addiction or psychological issues then semaglutide can't fix that.
Good evening, thank you for the kind message. I am aware that semaglutide has been approved for both, but Insurance companies don't see it that way, as of yet. I have indeed experienced all of the side effects I listed; that's the sole reason I wrote them out, in that way. I've very much had an intolerance to alcohol because of the drug. I just took a look at berberine; I will consider it, down the road.

I have had to deal with other issues, including hormonal regulation; I have had to deal with low testosterone, which has also been corrected. I appreciate your long, thoughtful posting.
 
Insurance companies don't see it that way, as of yet.

They are starting to change; my sister was approved for Wegovy a year ago. It's a slow rollout process but the benefits beyond diabetes management are undeniable.

I have indeed experienced all of the side effects I listed

Damn! I'm so sorry you experienced all of that. Yeah, you definitely shouldn't take it if your body rejects it that hard.

I have had to deal with other issues, including hormonal regulation

Given that GLPs are mimicking hormones, I can't help but wonder if preexisting issues with hormonal regulation is probably what leads to the worst side effects?
 
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They are starting to change; my sister was approved for Wegovy a year ago. It's a slow rollout process but the benefits beyond diabetes management are undeniable.



Damn! I'm so sorry you experienced all of that. Yeah, you definitely shouldn't take it if your body rejects it that hard.



Given that GLPs are mimicking hormones, I can't help but wonder if preexisting issues with hormonal regulation is probably what leads to the worst side effects?
No no, this was a preexisting issue; I was diagnosed with hypogonadism, years ago. My testosterone is now normal, resting at just under 700. Semaglutide, much like everything else, has played its part (however temporary) in getting me into a healthier state of being.
 
No no, this was a preexisting issue; I was diagnosed with hypogonadism, years ago. My testosterone is now normal, resting at just under 700. Semaglutide, much like everything else, has played its part (however temporary) in getting me into a healthier state of being.
Similar weight, also hypogonadism. Glad to hear you have gotten to a healthier state of being. Thought about going on one of these but worried about side effects like you experienced. Anyway good luck on your journey and congrats on your weightloss! I'm envious haha
 
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Similar weight, also hypogonadism. Glad to hear you have gotten to a healthier state of being. Thought about going on one of these but worried about side effects like you experienced. Anyway good luck on your journey and congrats on your weightloss! I'm envious haha
Thank you for the lovely message. What does your Doctor advise? What are you doing for your hypogonadism? Weight loss takes both dedication and patience, which are very difficult. My inspiration is my partner, who is height-weight proportionate.
 
So I used Sema to lose 90 pounds. What I learned is that life was MUCH harder at 330 then at 240.
I use that as my drive to stay lighter. I like to compete in bench press comps so there was a lot of strength lost along with that 90 pounds of fat so I almost hated losing the weight at points. What you need to do is find what you love about you at this weight and contrast it to something you hated when you were heavier. Sema is a tool, just like any other. It did its job, now it's time for you to do yours. Is that whole pizza worth the 9 months you spent losing what you did, or would a slice or 2 taste just as good but without the guilt. One thing you CANNOT do under any circumstance is start to feel guilty for gaining a couple pounds. Identify why and how you gained them, is it simply water retention from salty foods or is it stool retention because of a change in fiber, or did you actually consume 7000 more calories than you needed? Identify and adjust, don't let the guilt of a pound or 2 cause you to stress eat. Take it as a challenge and FIGHT! Good luck on your journey!